HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 3-Methoxycarbonyl-2-(1-naphthylmethylene)propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 3-[(Naphthalen-1-yl)methylidene]oxolane-2,5-dione | HCID 54316428 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-Methoxycarbonyl-2-(1-naphthylmethylene)propionic acid | HCID 54382754 | — |
Reaction Steps
A solution of 300 mg of 2-(1-naphthylmethylene)succinic anhydride and 18 ml of methyl alcohol in 30 ml of dry dichloromethane was heated under reflux for 5 hours. The reaction mixture was washed successively with a diluted hydrochloric acid and water, dried over anhydrous magnesium sulfate, and concentrated under reduced pressure to obtain 336 mg of 3-methoxycarbonyl-2-(1-naphthylmethylene)propionic acid as a white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04857650 |
| Source dataset | uspto-grants-1989_08 |
| ORD ID | ord-7c6f993985394140a48f50b225fe1c61 |
| Source note | uspto-grants-1989_08 |