反应详情

To a solution of 251 mg of the propionic acid compound in 10 ml of methyl alcohol was added 30 mg of a 10% palladium charcoal, and the mixture was hydrogenated under a hydrogen atmosphere at room temperature. After filtration of the catalyst, the reaction mixture was concentrated under reduced pressure to obtain 250 mg of 3-methoxycarbonyl-2-(1-naphthylmethyl)propionic acid as a white powder.

1. customwas hydrogenated under a hydrogen atmosphere at room temperature
2. filtrationAfter filtration of the catalyst
3. concentrationthe reaction mixture was concentrated under reduced pressure