Hydrochloric Acid → HCID 178509071, compound

HRID 1722928Notes

Reaction equation

HRID 1722928 reaction equation
N1C=CC=CC=1.C([N:10]1[C:14]([NH2:15])=[N:13][C:12]([S:16]([NH:19][C:20]2[C:25]([Cl:26])=[CH:24][CH:23]=[CH:22][C:21]=2[Cl:27])(=[O:18])=[O:17])=[N:11]1)(=O)C.Cl>[OH-].[Na+]>[NH2:15][C:14]1[NH:10][N:11]=[C:12]([S:16]([NH:19][C:20]2[C:25]([Cl:26])=[CH:24][CH:23]=[CH:22][C:21]=2[Cl:27])(=[O:18])=[O:17])[N:13]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 1049PyridineHCID 14255125HCID 14255125, compound

Product 1

HCID 178509071HCID 178509071, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

53.6 g (0.12 mol) of the pyridine salt of 1-acetyl-5-amino-N-(2,6-dichlorophenyl)-1,2,4-triazole-3-sulphonamide was dissolved in 200 ml 2N aqueous sodium hydroxide and stirred at room temperature for 10 minutes. With ice cooling it was brought to pH 5 with 2N hydrochloric acid. The crystals were separated, washed with a small amount of water and ether and dried in vacuo.

Workup

  1. customThe crystals were separated
  2. washwashed with a small amount of water and ether
  3. customdried in vacuo

Sources & evidence

ORD record
ord-01976a742fc44029a5f86882fb3c9319
Source dataset
uspto-grants-1989_08
Patent number
US04859231

Reaction notes

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