反应详情

Carnitine chloride (1.97 g; 0.01 moles) was dissolved in trifluoroacetic acid (10 cc). To the solution tert-butyl acetyl chloride (1.4 cc; 0.01 moles) was slowly added under stirring. The resulting mixture was kept under stirring at room temperature for 48 hours. To te mixture Et2O was added and the thus obtained precipitate was filtered off. The raw product was crystallized from isopropanol-ethyl ether, thus obtaining a pure product. MP 164°-165° C.

1. stirringunder stirring at room temperature for 48 hours
2. filtrationthe thus obtained precipitate was filtered off
3. customThe raw product was crystallized from isopropanol-ethyl ether
4. customthus obtaining a pure product