Thionyl Chloride → HCID 20026612, compound

Participants

Reaction Steps

(a-2) To a stirred solution of 112.13 parts of 2-phenyl-1-propyl-1H-benzimidazole-5-carboxylic acid in 525 parts of trichloromethane were added 142 parts of thionyl chloride. Stirring was continued for 30 minutes at reflux temperature. The reaction mixture was evaporated, yielding 134 parts (100%) of 2-phenyl-1-propyl-1H-benzimidazole-5-carbonyl chloride monohydrochloride as a residue (int. 58).

Provenance & Evidence