HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 20026743, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Hydrogen Sulfide | HCID 402 | — |
| Reactant | 4-(4-Chlorophenyl)-4-oxobutanenitrile | HCID 587352 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 20026743 | HCID 20026743 | — |
Reaction Steps
HCl and H2S gas are bubbled through a solution of the above nitrile (7.70 g, 40.0 mmol) in 100 ml of methanol at 10°-20° for 7 hours. The suspension is then stirred at RT overnight. It is dried, filtered, washed with ether and dried with suction under an N2 atmosphere to give 2-amino-5-(4-chlorophenyl)thiophene hydrochloric acid salt, a slightly purplish powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04859699 |
| Source dataset | uspto-grants-1989_08 |
| ORD ID | ord-635ba454883b498fbe2ee6a32cb8e999 |
| Source note | uspto-grants-1989_08 |