Ethanol → HCID 85590471, compound

Participants

Reaction Steps

A mixture of the above tetrahydrothiophene (5.70 g, 27.0 mmol), hydroxylamine HCl (2.81 g, 40.0 mmol) and barium carbonate (5.60 g) in 70 ml of ethanol is heated under reflux overnight. The solid is filtered and washed with 250 ml of hot ethanol. The filtrate is stripped of solvent, and the residue is diluted with ether and ethyl acetate, washed with water and with brine, dried and stripped of solvent to give 2-(4-chlorophenyl)-4-oxotetrahydrothiophene oxime.

Provenance & Evidence