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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1723269Generated: October 27, 2026

Methyl iodide → 1-(3,5-Difluorobenzyl)-2-methylmercaptoimidazole-5-carboxylic acid

https://huagongshe.com/reaction/1723269

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantSodium MethoxideHCID 10942334—
ReactantHCID 178524783HCID 178524783—
SolventMethanolHCID 887—
Product1-(3,5-Difluorobenzyl)-2-methylmercaptoimidazole-5-carboxylic acidHCID 14769734—

Reaction Steps

Reaction of 1-(3,5-difluorobenzyl)-2-mercaptoimidazole-5-carboxylic acid prepared as in Example 1 with methyl iodide and sodium methoxide in methanol by standard techniques yields 1-(3,5-difluorobenzyl)-2-methylmercaptoimidazole-5-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04859779
Source datasetuspto-grants-1989_08
ORD IDord-2428c5cfb6f04bf9a749ce8f24b9406a
Source noteuspto-grants-1989_08