Dimethylformamide → HCID 15314442, compound

Participants

Reaction Steps

2,3-Dihydrophthalazine-1,4-dione (0.02 mol) was added to a suspension of sodium hydride (0.04 mol; 50% solution in mineral oil) in anhydrous dimethylformamide (100 ml). To this was slowly added an excess amount of methyl iodide (0.05 mol). The mixture was stirred under reflux for 24 hours. The solvent was evaporated and the product purified by recrystallization from benzene. The purified product was obtained in a yield of 78 percent.

Provenance & Evidence