Hydrazine hydrate (1:1) → HCID 15046182, compound

HRID 1723319Notes

Reaction equation

HRID 1723319 reaction equation
O.[NH2:2][NH2:3].[Cl:4][C:5]1[CH:15]=[CH:14][CH:13]=[C:7]2[C:8]([O:10][C:11](=O)[C:6]=12)=[O:9]>C(O)C>[Cl:4][C:5]1[CH:15]=[CH:14][CH:13]=[C:7]2[C:6]=1[C:11](=[O:10])[NH:2][NH:3][C:8]2=[O:9]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 670143-Chlorophthalic anhydride

Product 1

HCID 15046182HCID 15046182, compoundYield 58%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 3-chlorophthalic anyhydride (0.02 mol) and hydrazine hydrate (0.02 mol) in dry ethanol (50 ml) was heated to reflux in a reaction flask. Reflux continued for several hours until the 3-chlorophthalic anhydride disappeared and a white crystalline solid deposited on the walls of the flask. The solid was filtered and recrystallized from ethanol to yield 5-chloro-2,3-dihydrophthalazine1,4-dione in a yield of 58 percent.

Workup

  1. temperaturewas heated
  2. temperatureto reflux in a reaction flask
  3. temperatureReflux
  4. filtrationThe solid was filtered
  5. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-f60f77123aff408cbf2cd2d08d831b56
Source dataset
uspto-grants-1989_08
Patent number
US04861778

Reaction notes

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