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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1723331Generated: October 29, 2026

4-(2-Chloroethyl)morpholine → 2-(2-Morpholinoethylthio)-3-phenyl-4(3H)-quinazolinone

https://huagongshe.com/reaction/1723331

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Chloroethyl)morpholineHCID 76727—
ReactantHCID 178515047HCID 178515047—
Product2-(2-Morpholinoethylthio)-3-phenyl-4(3H)-quinazolinoneHCID 1457515549.8%

Reaction Steps

The title compound was prepared in a yield of 49.8%, using 2-mercapto-3-phenyl-4(3H)-quinazolinone in place of 3-isobutyl-2-mercapto-4(3H)-quinazolinone and N-(2chloroethyl)morpholine in place of 2-chloromethylpyridine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04861780
Source datasetuspto-grants-1989_08
ORD IDord-e01b637d7978480482d83eb335aeb987
Source noteuspto-grants-1989_08