反应详情

5-(5-Acetyl-2-furanyl)pentanol (9.8 g), 13.1 g of triphenylphosphine and 100 ml of carbon tetrachloride were combined and heated at reflux for 4 hours. The reaction mixture was concentrated in vacuo, and the residue was dissolved in ether and filtered. The filtrate was concentrated and the residue distilled twice to give 2-(5-chloropentyl)-5-acetylfuran, b.p. 100°-102° C. (0.05 mm) in 60% yield.

1. temperatureheated
2. temperatureat reflux for 4 hours
3. concentrationThe reaction mixture was concentrated in vacuo
4. dissolutionthe residue was dissolved in ether
5. filtrationfiltered
6. concentrationThe filtrate was concentrated
7. distillationthe residue distilled twice