Methylamine → HCID 53906861, compound

HRID 1723463Notes

Reaction equation

HRID 1723463 reaction equation
[CH2:1]([C:4]12[CH2:10][CH:7]([CH:8]=[CH:9]1)[CH2:6][CH:5]2[C:11](Cl)=[O:12])[CH:2]=[CH2:3].[CH3:14][NH2:15]>CCOCC>[CH3:14][NH:15][C:11]([CH:5]1[CH2:6][CH:7]2[CH2:10][C:4]1([CH2:1][CH:2]=[CH2:3])[CH:9]=[CH:8]2)=[O:12]

Participants

4

Reactant 2

HCID 6329MethylamineHCID 20070591HCID 20070591, compound

Product 1

HCID 53906861HCID 53906861, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

With cooling, 9.8 g of allylbicyclo[2.2.1]hept-5-ene-2-carbonyl chloride are added dropwise to 50 ml of a 40% aqueous methylamine solution. After 1 hour at 20° C., 100 ml of ether are added. The organic phase is separated, and working up is effected as described in Example 4, affording 8.0 g (84% of theory) of a yellow liquid. For the purpose of characterisation, a sample is distilled in a bulb tube; nD20 =1.5160; η25 =420 mPas.

Workup

  1. temperatureWith cooling
  2. customThe organic phase is separated
  3. customaffording 8.0 g (84% of theory) of a yellow liquid
  4. distillationFor the purpose of characterisation, a sample is distilled in a bulb tube

Sources & evidence

ORD record
ord-6802442040bf4fa5aa23ebdc91b9f35c
Source dataset
uspto-grants-1989_08
Patent number
US04861885

Reaction notes

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