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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1723859Generated: November 2, 2026

Hydrogen Bromide → HCID 57420547, compound

https://huagongshe.com/reaction/1723859

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrogen BromideHCID 260—
ReactantNitrogenHCID 947—
Reactanttert-Butyl methyl etherHCID 15413—
ReactantHCID 11510935HCID 11510935—
SolventMethanolHCID 887—
ProductHCID 57420547HCID 57420547—

Reaction Steps

4.840 mg of concentrated hydrobromic acid was added to 0.89 ml of a solution of 1-(2-fluorophenyl)-3-(piperidin-4-yloxy)-1H-indazole in MeOH (concentration=10.3 mg/ml). The solution was placed under a stream of N2 gas until no solvent remained. Approximately 0.5 ml of MTBE was added and the sample was left open and stirred overnight. A white solid remained upon recovery.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07485636B2
Source datasetuspto-grants-2009_02
ORD IDord-10276e7162f24b6aa1b270477fd6737f
Source noteuspto-grants-2009_02