Potassium Cation → tert-butyl 4-((4-(N-(2-hydroxyethyl)-N-methylcarbamoyl)phenyl)(quinolin-8-yl)methylene)piperidine-1-carboxylate

HRID 172454Notes

Reaction equation

HRID 172454 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11](=[C:14]([c:15]2[cH:16][cH:17][c:18]([C:21]([N:22]([CH3:23])[CH2:24][CH2:25][OH:26])=[O:27])[cH:19][cH:20]2)[Br:28])[CH2:12][CH2:13]1.[CH:48]([OH:49])([CH3:50])[CH3:51].[K+:42].[K+:43].[O-:44][C:45]([O-:46])=[O:47].[n:29]1[cH:30][cH:31][cH:32][c:33]2[cH:34][cH:35][cH:36][c:37]([B:39]([OH:40])[OH:41])[c:38]12>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11](=[C:14]([c:15]2[cH:16][cH:17][c:18]([C:21]([N:22]([CH3:23])[CH2:24][CH2:25][OH:26])=[O:27])[cH:19][cH:20]2)[c:37]2[cH:36][cH:35][cH:34][c:33]3[cH:32][cH:31][cH:30][n:29][c:38]32)[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 3776IsopropanolHCID 19660Carbonate IonHCID 27343808-Quinolineboronic acidHCID 24897463HCID 24897463, compound

Product 1

HCID 24897464tert-butyl 4-((4-(N-(2-hydroxyethyl)-N-methylcarbamoyl)phenyl)(quinolin-8-yl)methylene)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-e7a18b2e29c540f480d96295ea424ac2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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