1-(2-Pyridyl)piperazine → HCID 10319871, compound

HRID 1724657Notes

Reaction equation

HRID 1724657 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[N:7]1[CH2:12][CH2:11][NH:10][CH2:9][CH2:8]1.[F:13][C:14]1[CH:19]=[CH:18][C:17]([S:20]([N:23]2[CH2:28][CH2:27][CH:26]([CH2:29]OS(C3C=CC(F)=CC=3)(=O)=O)[CH2:25][CH2:24]2)(=[O:22])=[O:21])=[CH:16][CH:15]=1>>[F:13][C:14]1[CH:15]=[CH:16][C:17]([S:20]([N:23]2[CH2:28][CH2:27][CH:26]([CH2:29][N:10]3[CH2:9][CH2:8][N:7]([C:2]4[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=4)[CH2:12][CH2:11]3)[CH2:25][CH2:24]2)(=[O:21])=[O:22])=[CH:18][CH:19]=1

Participants

3

Reactant 2

HCID 944591-(2-Pyridyl)piperazineHCID 86594848HCID 86594848, compound

Product 1

HCID 10319871HCID 10319871, compound

Procedure

Reaction of 1-pyridin-2-yl-piperazine and 4-fluoro-benzenesulfonic acid 1-(4-fluoro-benzenesulfonyl)-piperidin-4-ylmethyl ester as described in Example 1 gave the desired product, 1-[1-(4-Fluoro-benzenesulfonyl)-piperidin-4-ylmethyl]-4-pyridin-2-yl-piperazine.

Sources & evidence

ORD record
ord-cee5c22089ba4cf5b803c30efa0aad5f
Source dataset
uspto-grants-2009_02
Patent number
US07488731B2

Reaction notes

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