HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Trifluoroacetic acid → HCID 69081364, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Trifluoroacetic acid | HCID 6422 | — |
| Edukt | 4-acetylphenyl 3-tert-butoxycarbonyl-2,2-dimethyloxazolidine-4-(R)-carboxylate | HCID 69081870 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | HCID 69081364 | HCID 69081364 | — |
Reaktionsschritte
Under nitrogen, 4-acetylphenyl 3-tert-butoxycarbonyl-2,2-dimethyloxazolidine-4-(R)-carboxylate (440 mg) is dissolved in dichloromethane (15 ml), and trifluoroacetic acid (TFA; 8 ml) is added. After being subjected to agitation for 1 hour, the reaction mixture is concentrated and ether is added. The formed precipitate is filtered, then vacuum dried to obtain the desired product as a white powder (280 mg). Melting point: 115-118° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07488755B2 |
| Quelldatensatz | uspto-grants-2009_02 |
| ORD ID | ord-eaf5fcd2fbbd400187d408b2463c3d05 |
| Quellennotiz | uspto-grants-2009_02 |