Hydrogen Bromide → 4,4-Diphenyl-3-butenyl bromide

HRID 1724723ノート

反応式

HRID 1724723 の反応式
[CH:1]1([C:4]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)([C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=2)O)[CH2:3][CH2:2]1.[BrH:18]>O.ClCCl>[C:6]1([C:4]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:1][CH2:2][CH2:3][Br:18])[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1

参加物

5

反応物 2

HCID 260Hydrogen BromideHCID 79850alpha-Cyclopropyl-alpha-phenylbenzenemethanol

生成物 1

HCID 104017744,4-Diphenyl-3-butenyl bromide

試薬・触媒・溶媒 2

HCID 962Water溶媒HCID 6344Dichloromethane溶媒

実験手順

At 0° C., cyclopropyl-diphenyl-carbinol (10.0 g) is dissolved in a hydrogen bromide solution 48% (40 ml). After being subjected to agitation for 5 hours at 0° C., the medium is diluted with water and dichloromethane, then the organic phase is washed three times with water. The organic phase is dried on MgSO4, filtered and concentrated to obtain the expected product as an orange oil (11.89 g).

後処理

  1. washthe organic phase is washed three times with water
  2. customThe organic phase is dried on MgSO4
  3. filtrationfiltered
  4. concentrationconcentrated

出典と根拠

ORDレコード
ord-9a85e85389fd4a62a83eea49b410fe0f
出典データセット
uspto-grants-2009_02
特許番号
US07488755B2

反応ノート

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