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HRID1724808

反应详情

EQUATION

反应方程式

HRID 1724808 的结构方程式

REACTANTS

反应物

2
结构：CCOC(=O)c1ccc(C)[nH]1
HCID96598

1H-Pyrrole-2-carboxylic acid, 5-methyl-, ethyl ester

C8H11NO2

结构：O=C(Cl)C=Cc1ccc2ccccc2c1
HCID53928395

3-(Naphthalen-2-yl)prop-2-enoyl chloride

C13H9ClO

PRODUCTS

生成物

1
结构：CCOC(=O)c1cc(C(=O)C=Cc2ccc3ccccc3c2)c(C)[nH]1
HCID66922127

未命名化合物

PROCEDURE

实验过程

5-Methyl-4-(3-naphthalen-2-yl-acryloyl)-1H-pyrrole-2-carboxylic acid ethyl ester (132) was synthesized from 5-methyl-1H-pyrrole-2-carboxylic acid ethyl ester (107) and-3-naphthalen-2-yl-acryloyl chloride following the procedure described in Example 32. Reaction conditions: 1,2-dichloromethane/−40° C.→RT. Purification: no purification. LC/MS: 40%.

WORKUP

后处理

  1. customReaction conditions
  2. customPurification
  3. customno purification