反应详情

6-Methoxymethyl-3-nitro-pyridine-2,4-diamine (455 mg, 2.29 mmol) is dissolved in EtOH (50 mL) and 10% Pd/C (50 mg) is added. The mixture is hydrogenated at 50 psi for 2 hours. The reaction mixture is filtered through Celite and the Celite bed washed with EtOH (25 mL). The solvent is removed under reduced pressure to yield the title compound as an off-white solid.

1. filtrationThe reaction mixture is filtered through Celite
2. washthe Celite bed washed with EtOH (25 mL)
3. customThe solvent is removed under reduced pressure