HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → HCID 46203239, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | HCID 178516376 | HCID 178516376 | — |
| Product | HCID 46203239 | HCID 46203239 | — |
Reaction Steps
Reflux 7-[3-(trifluoromethyl)pyridin-2-yl]quinolin-4-ol (145 mg) for 2 hours in POCl3 (2 mL). Evaporate the solvent, then carefully neutralize with saturated NaHCO3, and extract with EtOAc. Dry-over Na2SO4, concentrate under vacuum to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07488740B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-be336268e8c946c8846801c5a4c5b613 |
| Source note | uspto-grants-2009_02 |