HCID 57562611, compound → HCID 57562606, compound

HRID 1725506Notes

Reaction equation

HRID 1725506 reaction equation
C([N:8]1[CH2:14][CH:13]([O:15][CH:16]2[CH2:21][CH2:20][CH2:19][CH2:18][O:17]2)[CH2:12][N:11](CC2C=CC=CC=2)[CH2:10][CH2:9]1)C1C=CC=CC=1>CO.[OH-].[OH-].[Pd+2]>[O:17]1[CH2:18][CH2:19][CH2:20][CH2:21][CH:16]1[O:15][CH:13]1[CH2:14][NH:8][CH2:9][CH2:10][NH:11][CH2:12]1

Participants

4

Reactant 1

HCID 57562611HCID 57562611, compound

Product 1

HCID 57562606HCID 57562606, compound

Reagents, catalysts & solvents 2

HCID 9942167Palladium hydroxideCatalystHCID 887MethanolSolvent

Procedure

3.06 g of 1,4-dibenzyl-6-(tetrahydro-2H-pyran-2-yloxy)-1,4-diazepane was dissolved in 50 ml of methanol and 1 g of a 20% palladium hydroxide on carbon catalyst was added thereto. The resulting mixture was stirred under a hydrogen atmosphere at ordinary pressure and room temperature for 5 hours. The reaction solution was filtered and the solvent was concentrated to give the title compound.

Workup

  1. filtrationThe reaction solution was filtered
  2. concentrationthe solvent was concentrated

Sources & evidence

ORD record
ord-57dea8fd485842d2b3dc6f88f074097f
Source dataset
uspto-grants-2009_02
Patent number
US07491720B2

Reaction notes

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