Hydrochloric Acid → 4-(1H-pyrrolo(2,3-b)pyridin-3-yl)piperidine

HRID 1725579Notes

Reaction equation

HRID 1725579 reaction equation
[NH:1]1[CH2:6][CH:5]=[C:4]([C:7]2[C:15]3[C:10](=[N:11][CH:12]=[CH:13][CH:14]=3)[NH:9][CH:8]=2)[CH2:3][CH2:2]1.Cl>[Pd].C(O)C>[NH:1]1[CH2:2][CH2:3][CH:4]([C:7]2[C:15]3[C:10](=[N:11][CH:12]=[CH:13][CH:14]=3)[NH:9][CH:8]=2)[CH2:5][CH2:6]1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 148220634-{1H-pyrrolo[2,3-b]pyridin-3-yl}-1,2,3,6-tetrahydropyridine

Product 1

HCID 55294774-(1H-pyrrolo(2,3-b)pyridin-3-yl)piperidine

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Preparation took place by hydrogenation of 3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine with palladium on carbon in ethanol with the addition of hydrochloric acid.

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-ac88b94884574d65a56717837c07fe33
Source dataset
uspto-grants-2009_02
Patent number
US07491729B2

Reaction notes

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