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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1725580Generated: October 30, 2026

1H-Tetrazole, 5-chloro-1-phenyl- → 1-(1-Phenyl-1H-tetrazol-5-YL)piperazine

https://huagongshe.com/reaction/1725580

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Tetrazole, 5-chloro-1-phenyl-HCID 84262—
Reactanttert-Butyl piperazine-1-carboxylateHCID 143452—
SolventDimethylformamideHCID 6228—
Product1-(1-Phenyl-1H-tetrazol-5-YL)piperazineHCID 3825578—

Reaction Steps

Preparation took place by reacting 5-chloro-1-phenyl-1H-tetrazole with tert-butyl piperazine-1-carboxylate in DMF at 40° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07491729B2
Source datasetuspto-grants-2009_02
ORD IDord-cf8a911380a94912a6559661905a8255
Source noteuspto-grants-2009_02