Nitric Acid → HCID 178418691, compound

Participants

Reaction Steps

To a solution of aniline (1.28 ml, 14 mmol) in ethanol (14 ml) was added cyanamide (1.25 ml, 16.1 mmol) and nitric acid (1 ml, 14 mmol), and the reaction was heated to reflux. After 16 hours, the reaction was cooled to room temperature and poured into diethyl ether. The resulting precipitate was filtered and dried to afford the title compound as a gray solid (2.50 g, 13 mmol, 90%). NMR (300 MHz, CD3OD): δ 7.47 (m, 2H), 7.36 (m, 1H), 7.30 (m, 2H).

Provenance & Evidence