Hydrochloric Acid → HCID 11305799, compound

HRID 1725780Notes

Reaction equation

HRID 1725780 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]([C:22]2([OH:28])[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]2)[C:9]([N:11]2[CH2:16][CH2:15][CH:14]([N:17]3[CH2:21][CH2:20][CH2:19][CH2:18]3)[CH2:13][CH2:12]2)=O)[CH:5]=[CH:6][CH:7]=1.[ClH:29]>>[ClH:1].[ClH:29].[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]([C:22]2([OH:28])[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]2)[CH2:9][N:11]2[CH2:16][CH2:15][CH:14]([N:17]3[CH2:18][CH2:19][CH2:20][CH2:21]3)[CH2:13][CH2:12]2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 68855471HCID 68855471, compound

Product 1

HCID 11305799HCID 11305799, compound

Procedure

In an analogous manner to Example 1, step 21-[1-(3-chlorophenyl)-2-(4-pyrrolidin-1-ylpiperidin-1-yl)ethyl]cyclohexanoldihydrochloride was prepared from 1-[1-(3-chlorophenyl)-2-(4-pyrrolidin-1-ylpiperidin-1-yl)-2-oxoethyl]cyclohexanol. MS (ESI) m/z 391/393 ([M+H]+); HRMS: calcd for C23H35ClN2O.2.00 HCl, 462.1971; found (ESI), 391.2497.

Sources & evidence

ORD record
ord-4ab97bae0d804f9c9e6265e330dcd75a
Source dataset
uspto-grants-2009_02
Patent number
US07491723B2

Reaction notes

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