HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Trifluoromethyl)phenol → 3-(4-Trifluoromethylphenoxy)dihydrofuran-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Trifluoromethyl)phenol | HCID 67874 | — |
| Reactant | 2(3H)-Furanone, 3-bromodihydro- | HCID 95463 | — |
| Product | 3-(4-Trifluoromethylphenoxy)dihydrofuran-2-one | HCID 11425108 | 46% |
Reaction Steps
The compound is prepared according to the experimental procedure described in Preparation 1, starting with α-bromo-γ-butyrolactone (6.7 g, 0.040 mol) and 4-trifluoromethylphenol (5.0 g, 0.031 mol) to give 3.51 g of the expected compound in the form of a white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07491747B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-c82ee625d54847c8a6a76e9928203bc3 |
| Source note | uspto-grants-2009_02 |