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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1726099Generated: October 31, 2026

Hydrochloric Acid → HCID 136055970, compound

https://huagongshe.com/reaction/1726099

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 57562498HCID 57562498—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 136055970HCID 13605597098.8%

Reaction Steps

1.0 g of 5-benzyloxy-3-[1-tert-butoxycarbonyl-5-(2-morpholin-4-ylethoxy)-1H-indol-2-yl]indazole-1-carboxylic acid tert-butyl ester are stirred at ambient temperature for 18 hours in 6 ml of a 4M hydrochloric acid solution in dioxane. The product is filtered through sintered glass, and rinsed with dioxane to obtain 692.4 mg of 5-benzyloxy-3-[5-(2-morpholin-4-ylethoxy)-1H-indol-2-yl]-1H-indazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07491710B2
Source datasetuspto-grants-2009_02
ORD IDord-280727d8d92a44fcb67b1a3e00629ea0
Source noteuspto-grants-2009_02