HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 136055970, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 57562498 | HCID 57562498 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 136055970 | HCID 136055970 | 98.8% |
Reaction Steps
1.0 g of 5-benzyloxy-3-[1-tert-butoxycarbonyl-5-(2-morpholin-4-ylethoxy)-1H-indol-2-yl]indazole-1-carboxylic acid tert-butyl ester are stirred at ambient temperature for 18 hours in 6 ml of a 4M hydrochloric acid solution in dioxane. The product is filtered through sintered glass, and rinsed with dioxane to obtain 692.4 mg of 5-benzyloxy-3-[5-(2-morpholin-4-ylethoxy)-1H-indol-2-yl]-1H-indazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07491710B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-280727d8d92a44fcb67b1a3e00629ea0 |
| Source note | uspto-grants-2009_02 |