Trifluoroacetic acid → HCID 136056001, compound

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Reaction Steps

The compound {2-[2-(5-benzyloxy-1H-indazol-3-yl)-1H-indol-6-yloxy]ethyl}diethylamine is prepared in the following way: 390 mg of 5-benzyloxy-3-[1-tert-butoxycarbonyl-6-(2-diethylaminoethoxy)-1H-indol-2-yl]-indazole-1-carboxylic acid tert-butyl ester in solution in 5 ml of dichloromethane and 2 ml of trifluoroacetic acid are stirred at ambient temperature for 20 hours. The solvent is evaporated off under vacuum in a rotary evaporator to obtain 480 mg of {2-[2-(5-benzyloxy-1H-indazol-3-yl)-1-indol-6-yloxy]ethyl}diethylamine in the form of a trifluoroacetate salt.

Provenance & Evidence