HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
tert-Butyl 4-oxopiperidine-1-carboxylate → 4-[4-(2-Methoxy-ethoxy)-phenylamino]-piperidine-1-carboxylic acid tert-butyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | tert-Butyl 4-oxopiperidine-1-carboxylate | HCID 735900 | — |
| Edukt | 4-(2-Methoxyethoxy)aniline | HCID 3879885 | — |
| Produkt | 4-[4-(2-Methoxy-ethoxy)-phenylamino]-piperidine-1-carboxylic acid tert-butyl ester | HCID 68970494 | 86,9% |
Reaktionsschritte
Using general procedure A, 4-(2-methoxy-ethoxy)-phenylamine (Ishidate; Maruyoma, Chem. Abstr., 1952, 8810) (1.15 g, 6.84 mmol) and 1-Boc-4-piperidone (1.36 g, 6.83 mmol) afforded 4-[4-(2-methoxy-ethoxy)-phenylamino]-piperidine-1-carboxylic acid tert-butyl ester (2.08 g, 86%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07491735B2 |
| Quelldatensatz | uspto-grants-2009_02 |
| ORD ID | ord-0f80fc09251d4a52839540336deeb0f3 |
| Quellennotiz | uspto-grants-2009_02 |