2-(3-Oxobutyl)isoindoline-1,3-dione → HCID 68971694, compound

Participants

Reaction Steps

Using general procedure B with the above amine (18 mg, 0.049 mmol) and 2-(3-oxo-butyl)-isoindole-1,3-dione (21 mg, 0.098 mmol) and then using general procedure D afforded 3-{4-[4-fluoro-2-(4-trifluoromethyl-phenyl)-benzo[1,3]dioxol-2-yl]-piperidin-1-yl}-butylamine as a white solid (11 mg, 52% over 2 steps).

Provenance & Evidence