HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Trifluoromethoxy)aniline → HCID 68974486, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Trifluoromethoxy)aniline | HCID 600848 | — |
| Reactant | (betaR)-beta-Methyl-4-oxo-1-piperidinepropanenitrile | HCID 68972438 | — |
| Product | HCID 68974486 | HCID 68974486 | 113% |
Reaction Steps
Using general procedure A, (R)-3-(4-oxo-piperidin-1-yl)-butyronitrile (2.0 g, 12 mmol) and 4-(trifluoromethoxy)aniline (1.34 mL, 10.0 mmol) gave (R)-3-[4-(4-trifluoromethoxy-phenylamino)-piperidin-1-yl]-butyronitrile as a pale yellow solid (3.7 g, 94%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07491735B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-d5dcb8a2a74c4d2b81f8a916d57bb792 |
| Source note | uspto-grants-2009_02 |