Diisopropylethylamine → HCID 86610852, compound

Participants

Role	Name	HCID	Charge
Reactant	Diisopropylethylamine	HCID 81531	—
Reactant	4-(4-chlorophenyl)-2-phenyl-1,3-thiazole-5-carboxylic Acid	HCID 5284560	—
Reactant	1-[4-(Pyrimidin-2-YL)piperazin-1-YL]propan-2-amine	HCID 20075507	—
Product	HCID 86610852	HCID 86610852	—

Reaction Steps

Proceeding as set forth in part (A) above, but substituting 4-methyl-2-pyridin-2-yl-thiazole-5-carboxylic acid for 2-phenyl-4-(4-chlorophenyl)-thiazole-5-carboxylic acid and substituting intermediate XIIId and DIEA (0.03 mL) for 1-methyl-2-(4-pyrimidin-2-yl-piperazin-1-yl)ethyl amine, the compound 2-(pyrid-2-yl)-4-methyl-thiazole-5-carboxylic acid [1-methyl-2-(4-pyrimidin-2-yl-piperazin-1-yl)-ethyl]-amide (compound 31) was prepared. M+H=424

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07491821B2
Source dataset	uspto-grants-2009_02
ORD ID	ord-6e2e13ab5c874854a173eabae600691c
Source note	uspto-grants-2009_02