2-(2,4,6-Trimethylphenyl)propan-2-ol → 2-Isopropenyl-1,3,5-trimethylbenzene

HRID 1726851Notes

Reaction equation

HRID 1726851 reaction equation
[C:1]1([CH3:13])[CH:6]=[C:5]([CH3:7])[CH:4]=[C:3]([CH3:8])[C:2]=1[C:9](O)([CH3:11])[CH3:10]>C1COCC1>[CH3:11][C:9]([C:2]1[C:3]([CH3:8])=[CH:4][C:5]([CH3:7])=[CH:6][C:1]=1[CH3:13])=[CH2:10]

Participants

3

Reactant 1

HCID 2930032-(2,4,6-Trimethylphenyl)propan-2-ol

Product 1

HCID 5189862-Isopropenyl-1,3,5-trimethylbenzeneYield 44.6%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The same experiment as in Example 4 was carried out, except for using 50 ml of THF instead of 50 ml of CPME. The resulting reaction mixture was analyzed by gas chromatography to confirm that 2-mesityl-2-propanol and α-methyl-2,4,6-trimethylstyrene were obtained in a yield of 44.6% and 33.1%, respectively.

Workup

  1. customThe resulting reaction mixture

Sources & evidence

ORD record
ord-74d3b2bfbeb1453ebd0319afd3d8ebd8
Source dataset
uspto-grants-2009_02
Patent number
US07494962B2

Reaction notes

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