Sodium Iodide → HCID 68963943, compound

HRID 1726928Notes

Reaction equation

HRID 1726928 reaction equation
[CH2:1]([N:5]1[C:10](=[O:11])[CH2:9][N:8]([C:12]([O:14][CH2:15]Cl)=[O:13])[C:7]([C:17]2[CH:22]=[C:21]([Cl:23])[CH:20]=[C:19]([Cl:24])[CH:18]=2)=[N:6]1)[CH2:2][CH2:3][CH3:4].[I-:25].[Na+]>CC(C)=O>[CH2:1]([N:5]1[C:10](=[O:11])[CH2:9][N:8]([C:12]([O:14][CH2:15][I:25])=[O:13])[C:7]([C:17]2[CH:22]=[C:21]([Cl:23])[CH:20]=[C:19]([Cl:24])[CH:18]=2)=[N:6]1)[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 5238Sodium IodideHCID 68956623HCID 68956623, compound

Product 1

HCID 68963943HCID 68963943, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

1-(n-Butyl)-3-(3,5-dichlorophenyl)-4-(chloromethyloxycarbonyl)-4,5-dihydro-1,2,4-triazin-6-one was treated with sodium iodide in acetone as described in Folkmann, M.; Lund, F. J. Synthesis 1990, 1159 to give 1-(n-butyl)-3-(3,5-dichlorophenyl)-4-(iodomethyloxycarbonyl)-4,5-dihydro-1,2,4-triazin-6-one.

Workup

  1. customSynthesis 1990, 1159

Sources & evidence

ORD record
ord-b307af60d5bc4be5b3ea34f81cc3321a
Source dataset
uspto-grants-2009_02
Patent number
US07494996B2

Reaction notes

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