Methanol → 2-Amino-5-chloro-alpha-(3-tert-butoxycarbonylaminomethylphenyl)benzyl alcohol
Reaction equation
[BH4-:26].[CH2:28]([O:29][C:30](=[O:31])[CH3:32])[CH3:33].[CH3:34][OH:35].[NH2:1][c:2]1[c:3]([C:4](=[O:5])[c:6]2[cH:7][c:8]([CH2:12][NH:13][C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[cH:9][cH:10][cH:11]2)[cH:21][c:22]([Cl:25])[cH:23][cH:24]1.[Na+:27]>>[NH2:1][c:2]1[c:3]([CH:4]([OH:5])[c:6]2[cH:7][c:8]([CH2:12][NH:13][C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[cH:9][cH:10][cH:11]2)[cH:21][c:22]([Cl:25])[cH:23][cH:24]1Participants
6
Sources & evidence
- ORD record
- ord-27d6858ba6c94be6aad2eb33f505055c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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