3-Chloromethyl-2-methyl-6-(4-trifluoromethyl-phenyl)-pyridine → HCID 69036918, compound

Participants

Reaction Steps

In analogy to the procedures described in example 5C] and 5D], 2-methyl-2-(4-methylamino-5,6,7,8-tetrahydro-naphthalen-1-yloxy)-propionic acid ethyl ester was reacted with 3-chloromethyl-2-methyl-6-(4-trifluoromethyl-phenyl)-pyridine (example 4G]) to give 2-methyl-2-(4-{methyl-[2-methyl-6-(4-trifluoromethyl-phenyl)-pyridin-3-ylmethyl]-amino}-5,6,7,8-tetrahydro-naphthalen-1-yloxy)-propionic acid ethyl ester, which was subsequently saponified to yield the title compound as colorless solid.

Provenance & Evidence