HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-3-fluorobenzotrifluoride → 1-(2-Fluoro-4-(trifluoromethyl)phenyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-3-fluorobenzotrifluoride | HCID 142414 | — |
| Reactant | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| Product | 1-(2-Fluoro-4-(trifluoromethyl)phenyl)piperazine | HCID 46837495 | — |
Reaction Steps
The compound 1-(2-fluoro-4-trifluoromethyl-phenyl)-piperazine is synthesized according to the procedure outlined in Example 26 steps 1 and 2 using t-butyl-1-piperazine-carboxylate and 1-bromo-2-fluoro-4-trifluoromethyl-benzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07494999B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-00daf392c2fa4aab8b16b27a2be078dc |
| Source note | uspto-grants-2009_02 |