Sodium Carbonate → HCID 16097276, compound

HRID 1727093Notes

Reaction equation

HRID 1727093 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][N:11]2[CH2:15][CH2:14][C:13]([CH2:17][N:18]([CH3:32])[C:19]3[CH:31]=[CH:30][C:22]([C:23]([O:25]C(C)(C)C)=[O:24])=[CH:21][CH:20]=3)([OH:16])[CH2:12]2)=[CH:5][CH:4]=1)#[N:2].C(=O)([O-])[O-].[Na+].[Na+]>Cl>[C:1]([C:3]1[CH:4]=[CH:5][C:6]([CH2:9][CH2:10][N:11]2[CH2:15][CH2:14][C:13]([CH2:17][N:18]([CH3:32])[C:19]3[CH:20]=[CH:21][C:22]([C:23]([OH:25])=[O:24])=[CH:30][CH:31]=3)([OH:16])[CH2:12]2)=[CH:7][CH:8]=1)#[N:2]

Participants

4

Reactant 2

HCID 10340Sodium CarbonateHCID 23085065HCID 23085065, compound

Product 1

HCID 16097276HCID 16097276, compoundYield 40.7%

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

The compound (1.00 g) obtained in Example 8 was dissolved in 6 N hydrochloric acid (2.5 mL), followed by stirring at room temperature overnight. The mixture was treated with sodium carbonate to be adjusted to pH 7, the precipitate was collected by filtration, was washed with water, and was dried to yield the titled compound (0.355 g).

Workup

  1. filtrationthe precipitate was collected by filtration
  2. washwas washed with water
  3. customwas dried

Sources & evidence

ORD record
ord-4e11ff9b3f1b4f2bb14a01ecdf4cbe08
Source dataset
uspto-grants-2009_02
Patent number
US07494987B2

Reaction notes

Loading…