Hydrochloric Acid → HCID 67369924, compound

HRID 1727098Notes

Reaction equation

HRID 1727098 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][N:11]2[CH2:16][CH2:15][C:14]([CH2:18][N:19]([CH3:30])[C:20]3[CH:28]=[CH:27][C:23]([C:24]([OH:26])=[O:25])=[CH:22][C:21]=3[CH3:29])([OH:17])[CH2:13][CH2:12]2)=[CH:5][CH:4]=1)#[N:2].[ClH:31]>O>[ClH:31].[C:1]([C:3]1[CH:4]=[CH:5][C:6]([CH2:9][CH2:10][N:11]2[CH2:16][CH2:15][C:14]([CH2:18][N:19]([CH3:30])[C:20]3[CH:28]=[CH:27][C:23]([C:24]([OH:26])=[O:25])=[CH:22][C:21]=3[CH3:29])([OH:17])[CH2:13][CH2:12]2)=[CH:7][CH:8]=1)#[N:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 67369925HCID 67369925, compound

Product 1

HCID 67369924HCID 67369924, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The compound (310 mg) obtained in Example 3 was suspended in water (15 mL) and was dissolved therein by addition of 1 N hydrochloric acid (3.0 mL) with heating under reflux. After cooling, the solvent was removed under reduced pressure, the residue was pulverized, was dried under reduced pressure to yield the titled compound (274 mg) as a powder.

Workup

  1. dissolutionwas dissolved
  2. temperaturewith heating
  3. temperatureunder reflux
  4. temperatureAfter cooling
  5. customthe solvent was removed under reduced pressure
  6. customwas dried under reduced pressure

Sources & evidence

ORD record
ord-893b2729303f4054a36a237dba7d7ee5
Source dataset
uspto-grants-2009_02
Patent number
US07494987B2

Reaction notes

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