反应详情

A mixture of 4-benzyloxy-3-cyclopentyloxybenzaldehyde (6.3 g, 21.3 mmol) in AcOH (13 mL) and CH3NO2 (5.8 mL, 106.5 mmol) was created. NH4OAc (3.3 g, 42.5 mmol) was added and the mixture was heated under reflux for 2 h. After cooling to r.t., the mixture was extracted with CH2Cl2. The organic layer separated and washed with water, sat.

1. temperaturethe mixture was heated
2. temperatureunder reflux for 2 h
3. extractionthe mixture was extracted with CH2Cl2
4. customThe organic layer separated
5. washwashed with water