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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1727158Generated: November 2, 2026

Trifluoroacetic acid → HCID 68829433, compound

https://huagongshe.com/reaction/1727158

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 68828139HCID 68828139—
ProductHCID 68829433HCID 68829433—

Reaction Conditions

Temperature100 °C

Reaction Steps

Crude product of 6-{4-[3-(2-cyanophenoxy)-4-methoxyphenyl]-2-oxo-pyrrolidin-1-yl}pyridine-2-carboxylic acid bis-(4-methoxy-benzyl)-amide was added to a TFA (0.5 mL) solution and heated to 100° C. for 8 h. After cooling down to r.t., the mixture was concentrated and purified by preparative LC-MS to provide the desired product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07495016B2
Source datasetuspto-grants-2009_02
ORD IDord-f116e8aeb6c3487b863be44509c5d36d
Source noteuspto-grants-2009_02