Hydrochloric Acid → HCID 69058462, compound

Participants

Reaction Steps

tert-Butyl 3-[(2-pyridinylsulfanyl)methyl]-1-piperidinecarboxylate (Preparation 51, 1.0 g, 3.2 mmol) in hydrogen chloride (4 M solution in dioxane, 8.1 ml) was stirred under nitrogen at room temperature. After 25 min a white solid precipitated out of solution. Diethyl ether was added and the reaction mixture was filtered and the solid washed with diethyl ether. The title compound was obtained as a solid (0.81 g, 100%).

Provenance & Evidence