HCID 69053917, compound → HCID 69060894, compound

HRID 1727203Notes

Reaction equation

HRID 1727203 reaction equation
[CH2:1]([NH:5][C:6](=[O:21])[O:7][CH:8]1[CH2:13][CH2:12][N:11](CC2C=CC=CC=2)[CH2:10][CH2:9]1)[CH2:2][CH2:3][CH3:4]>C(O)C.[Pd]>[CH2:1]([NH:5][C:6](=[O:21])[O:7][CH:8]1[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 1

HCID 69053917HCID 69053917, compound

Product 1

HCID 69060894HCID 69060894, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

1-(Phenylmethyl)piperidin-4-yl butylcarbamate (Preparation 109, 13.0 g) in ethanol (100 ml) containing palladium (5% on carbon) was hydrogenated at 60 psi to give the title compound as a green oil that solidified upon standing.

Sources & evidence

ORD record
ord-cc394d9de4564166b92d281de96e1a5d
Source dataset
uspto-grants-2009_02
Patent number
US07494992B2

Reaction notes

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