m-Chloroperbenzoic acid → HCID 178526236, compound

HRID 1727777Notes

Reaction equation

HRID 1727777 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]2[NH:8][CH:9]=[CH:10][C:3]=12.ClC1C=CC=C(C(OO)=[O:19])C=1>C(OCC)C>[Br:1][C:2]1[CH:7]=[CH:6][N+:5]([O-:19])=[C:4]2[NH:8][CH:9]=[CH:10][C:3]=12

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 222736434-Bromo-1H-pyrrolo[2,3-b]pyridine

Product 1

HCID 178526236HCID 178526236, compoundYield 87%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

To a solution of 4-bromo-1H-pyrrolo[2,3-b]pyridine (25 mmol) in diethyl ether (400 mL) under nitrogen at room temperature was added m-chloroperbenzoic acid (40 mmol). The reaction was stirred for 2.5 h. The resultant precipitate was filtered and washed with cold ether (50 mL) to give the title compound as an off-white solid (87%). ESMS [M+H]+: 213.2

Workup

  1. filtrationThe resultant precipitate was filtered
  2. washwashed with cold ether (50 mL)

Sources & evidence

ORD record
ord-dc5b0b98d1a1474d8857c5b48f311cc1
Source dataset
uspto-grants-2009_02
Patent number
US07495102B2

Reaction notes

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