HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 23022741, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | HCID 23022742 | HCID 23022742 | — |
| Catalyst | Hydrochloride methanol | HCID 21893726 | — |
| Product | HCID 23022741 | HCID 23022741 | — |
Reaction Steps
1-(3,3-Dimethyl-butyl)-3-{2-fluoro-4-[6-methoxy-7-(2-morpholin-4-yl-ethoxy)-quinolin-4-yloxy]-phenyl}-urea (42.7 mg) was dissolved in chloroform (1 ml) and methanol (1 ml) to prepare a solution. To the solution was added 10 drops of 10% hydrogen chloride-methanol with a Pasteur pipette. The mixture was concentrated by an evaporator, and the concentrate was dried by means of a vacuum pump to give a hydride compound (48.9 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07495104B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-2a282fab870c476bb3826dca51d62e02 |
| Source note | uspto-grants-2009_02 |