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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1727873Generated: November 2, 2026

Methanol → HCID 23022741, compound

https://huagongshe.com/reaction/1727873

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantChloroformHCID 6212—
ReactantHCID 23022742HCID 23022742—
CatalystHydrochloride methanolHCID 21893726—
ProductHCID 23022741HCID 23022741—

Reaction Steps

1-(3,3-Dimethyl-butyl)-3-{2-fluoro-4-[6-methoxy-7-(2-morpholin-4-yl-ethoxy)-quinolin-4-yloxy]-phenyl}-urea (42.7 mg) was dissolved in chloroform (1 ml) and methanol (1 ml) to prepare a solution. To the solution was added 10 drops of 10% hydrogen chloride-methanol with a Pasteur pipette. The mixture was concentrated by an evaporator, and the concentrate was dried by means of a vacuum pump to give a hydride compound (48.9 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07495104B2
Source datasetuspto-grants-2009_02
ORD IDord-2a282fab870c476bb3826dca51d62e02
Source noteuspto-grants-2009_02