Methanol → HCID 23022689, compound

Participants

Reaction Steps

Methanol (20 ml) and chloroform (2 ml) were added to 1-(3,3-dimethyl-butyl)-3-{2-fluoro-4-[6-methoxy-7-(2-piperidin-1-yl-ethoxy)-quinolin-4-yloxy]-phenyl}-urea to prepare a solution. Hydrogen chloride-methanol was added to the solution, and the mixture was acidified and was concentrated. Diethyl ether was added to the residue, and mixture was filtrated to give the title compound (1.75 g, yield 91%).

Provenance & Evidence