Methanol → 1-[4-(6,7-Dimethoxy-quinolin-4-yloxy)-phenyl]-3-(3,3-dimethyl-butyl)-urea hydrochloride

Participants

Reaction Steps

Methanol (20 ml) and chloroform (2 ml) were added to 1-[4-(6,7-dimethoxy-quinolin-4-yloxy)-phenyl]-3-(3,3-dimethyl-butyl)-urea to prepare a solution. The solution was acidified by the addition of hydrogen chloride-methanol, and the acidified solution was concentrated. Diethyl ether was added to the residue, and the mixture was filtrated to give the title compound (1.75 g, yield 91%).

Provenance & Evidence