HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → HCID 12694356, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Ethyl 2-(diethoxyphosphoryl)butanoate | HCID 229053 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | HCID 12694356 | HCID 12694356 | 73% |
Reaction Steps
In a manner similar to the method described in example 102a, triethyl 2-phosphonobutyrate (25.2 g, 0.1 mol) was reacted with NaH (2.64 g, 0.11 mol), and then acetone (5.8 g, 0.1 mol) in dimethoxyethane to give 2-ethyl-3-methyl-but-2-enoic acid ethyl ester as colorless oil (Yield: 11.4 g, 73%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07495007B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-e85e7df7ec7841788a5116ae30c0124e |
| Source note | uspto-grants-2009_02 |