Potassium Carbonate → HCID 57566093, compound

HRID 1728120Notes

Reaction equation

HRID 1728120 reaction equation
[CH2:1]([C:3]1[CH:4]=[CH:5][C:6]([OH:11])=[C:7]([CH:10]=1)[CH:8]=[O:9])[CH3:2].C([O-])([O-])=O.[K+].[K+].Br[CH2:19][CH2:20][O:21][Si:22]([C:25]([CH3:28])([CH3:27])[CH3:26])([CH3:24])[CH3:23]>>[C:25]([Si:22]([CH3:24])([CH3:23])[O:21][CH2:20][CH2:19][O:11][C:6]1[CH:5]=[CH:4][C:3]([CH2:1][CH3:2])=[CH:10][C:7]=1[CH:8]=[O:9])([CH3:28])([CH3:27])[CH3:26]

Participants

4

Reactant 3

HCID 11430Potassium CarbonateHCID 3608067(2-Bromoethoxy)-tert-butyldimethylsilaneHCID 64298115-Ethyl-2-hydroxybenzaldehyde

Product 1

HCID 57566093HCID 57566093, compoundYield 92.7%

Procedure

In a manner similar to the method described in example 130a, 5-ethyl-2-hydroxy-benzaldehyde (4.75 g, 31.7 mmol) was reacted with K2CO3 (13.1 g, 95.1 mmol) and (2-bromo-ethoxy)-tert-butyl-dimethyl-silane (9.09 g, 38.0 mmol) to give 2-[2-(tert-Butyl-dimethyl-silanyloxy)-ethoxy]-5-ethyl-benzaldehyde as dark brown oil (9.0 g, 92.7%).

Sources & evidence

ORD record
ord-d74612e2f584437d881aafc0d36357e7
Source dataset
uspto-grants-2009_02
Patent number
US07495007B2

Reaction notes

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